Kif5a Mouse shRNA Plasmid (Locus ID 16572)
Specifications
| Product Data | |
| Locus ID | 16572 |
|---|---|
| Synonyms | D10Bwg0738e; Khc; Kif5; Kns; mKIAA4086 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Kif5a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16572). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC058396, NM_001039000, NM_008447, NM_008447.1, NM_008447.2, NM_008447.3, NM_008447.4, NM_001039000.1, NM_001039000.2, NM_001039000.3, NM_001039000.4, BC027115, BC028563 |
| UniProt ID | P33175 |
| Summary | Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (PubMed:12682084). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons (PubMed:21976701). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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