Sfxn1 Mouse shRNA Plasmid (Locus ID 14057)
Specifications
| Product Data | |
| Locus ID | 14057 |
|---|---|
| Synonyms | 2810002O05Rik; A930015P12Rik; f |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Sfxn1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 14057). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC005743, NM_027324, NM_027324.1, NM_027324.2, NM_027324.3, NM_027324.4, NM_027324.5 |
| UniProt ID | Q99JR1 |
| Summary | Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (By similarity). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (By similarity). Transports both D-serine and L-serine (By similarity). Also able to transport other amino-acids, such as alanine (By similarity). May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (PubMed:11274051).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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