Snrpn Mouse shRNA Plasmid (Locus ID 20646)
Specifications
| Product Data | |
| Locus ID | 20646 |
|---|---|
| Synonyms | 2410045I01Rik; HCERN3; Peg; Peg4; Pwc; sm-D; SMN; snRNP-N |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Snrpn - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 20646). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC019589, BC024880, NM_001082961, NM_001082962, NM_013670, NM_001082962.1, NM_001082962.2, NM_001082961.1, NM_001082961.2, NM_013670.1, NM_013670.2, NM_013670.3, NM_013670.4, BC069894 |
| UniProt ID | P63163 |
| Summary | This locus represents a paternally-expressed imprinted gene that encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing. Genomic and genetic changes in this region result in growth defects and lethality; the corresponding region in human is the critical region for Prader-Willi Syndrome. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants may be bicistronic and also encode the SNRPN upstream reading frame protein (Snurf) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (Snhg14) may originate from the promoters at this locus and incorporate exons shared with this gene. provided by RefSeq, Mar 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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