Cdt1 Mouse shRNA Plasmid (Locus ID 67177)
Specifications
| Product Data | |
| Locus ID | 67177 |
|---|---|
| Synonyms | 2610318F11Rik; AW545653; C76791; Ris2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Cdt1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 67177). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC048076, NM_026014, NM_026014.1, NM_026014.2, NM_026014.3, BC013842, BC024485 |
| UniProt ID | Q8R4E9 |
| Summary | Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments (By similarity). Potential oncogene (PubMed:11850834).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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