Dyrk1b Mouse shRNA Plasmid (Locus ID 13549)
Specifications
| Product Data | |
| Locus ID | 13549 |
|---|---|
| Synonyms | Mirk |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dyrk1b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 13549). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC019545, NM_001037957, NM_001271370, NM_010092, NM_001037957.1, NM_001037957.2, NM_001037957.3, NM_010092.1, NM_010092.2, NM_001271370.1 |
| UniProt ID | Q9Z188 |
| Summary | Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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