Arhgdig Mouse shRNA Plasmid (Locus ID 14570)
Specifications
| Product Data | |
| Locus ID | 14570 |
|---|---|
| Synonyms | Gdi5; Rho-GDI-3; Rho-GDI2; RIP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Arhgdig - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 14570). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC002032, NM_008113, NM_008113.1, NM_008113.2, NM_008113.3, BC158003 |
| UniProt ID | Q62160 |
| Summary | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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