Kcnj16 Mouse shRNA Plasmid (Locus ID 16517)
Specifications
| Product Data | |
| Locus ID | 16517 |
|---|---|
| Synonyms | 6430410F18Rik; AI132396; Kir5.1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Kcnj16 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16517). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC033442, BC092296, NM_001252207, NM_001252208, NM_001252209, NM_001252210, NM_010604, NM_010604.1, NM_010604.2, NM_010604.3, NM_001252207.1, NM_001252208.1, NM_001252209.1, NM_001252209.2, NM_001252210.1, NM_001252210.2 |
| UniProt ID | Q9Z307 |
| Summary | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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