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Myct1 Mouse shRNA Plasmid (Locus ID 68632)

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SKU
TR513832
Myct1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 68632
Synonyms 1110020B04Rik; AI225941; AI642973; Mtmc1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Myct1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 68632). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC096559, NM_026793, NM_026793.1, NM_026793.2, BM569633
UniProt ID Q8R411
Summary May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability and inhibition of hematopoietic differentiation.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc
Graves, Metukuri, Scott et al
J Biol Chem (2009) 284 (10), 6520-9 DOI: 10.1074/jbc.M807564200
AI Summary: In this study, OriGene’s Prx1 (OriGene, Cat# SC119827) and Prx5 (OriGene, Cat# SC119831) expression plasmids were used to investigate the roles of peroxiredoxins in regulating reactive oxygen species homeostasis and their interaction with c-Myc.
Showing 1-1 of 1 papers.
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