Elovl1 Mouse shRNA Plasmid (Locus ID 54325)
Specifications
| Product Data | |
| Locus ID | 54325 |
|---|---|
| Synonyms | AA407424; BB151133; Ssc1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Elovl1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54325). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC006735, BC096673, NM_001039175, NM_001039176, NM_019422, NM_001039175.1, NM_001039175.2, NM_019422.1, NM_019422.2, NM_019422.3, NM_001039176.1, NM_001039176.2, BM445297 |
| UniProt ID | Q9JLJ5 |
| Summary | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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