Csf1 Mouse shRNA Plasmid (Locus ID 12977)
Specifications
| Product Data | |
| Locus ID | 12977 |
|---|---|
| Synonyms | C87615; Csfm; MCSF; op |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Csf1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 12977). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC066187, BC066200, BC066205, NM_001113529, NM_001113530, NM_007778, NM_001113530.1, NM_007778.1, NM_007778.2, NM_007778.3, NM_007778.4, NM_001113529.1, BC025593 |
| UniProt ID | P07141 |
| Summary | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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