Ppp2r2b Mouse shRNA Plasmid (Locus ID 72930)
Specifications
| Product Data | |
| Locus ID | 72930 |
|---|---|
| Synonyms | 2900026H06Rik; 6330404L05Rik; E130009M08Rik; PP2A-PR55B; PR55-BETA; SCA12 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ppp2r2b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 72930). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC026686, BC088979, NM_027531, NM_028392, NR_073583, NM_027531.1, NM_028392.1, NM_028392.2, NM_028392.3, BC066007, BC085147, NM_027531.2 |
| UniProt ID | Q6ZWR4 |
| Summary | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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