Dis3l Mouse shRNA Plasmid (Locus ID 213550)
Specifications
| Product Data | |
| Locus ID | 213550 |
|---|---|
| Synonyms | AV340375 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dis3l - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 213550). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC056939, NM_001001295, NM_001177784, NM_172519, NM_001177784.1, NM_001001295.1, NM_001001295.2, NM_172519.1, NM_172519.2, NM_172519.3, BM900123 |
| UniProt ID | Q8C0S1 |
| Summary | Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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