Notum Mouse shRNA Plasmid (Locus ID 77583)

SKU
TR512881
Notum - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 77583
Synonyms 5730593N15Rik
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Notum - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 77583). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC025832, NM_175263, NM_175263.1, NM_175263.2, NM_175263.3, NM_175263.4
UniProt ID Q8R116
Summary Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Notum as a Crucial Regulator of Matrix Integrity in Dentinogenesis
Choi, Jeong, Adasooriya et al
J Cell Physiol (2025) 240 (7), e70070 DOI: 10.1002/jcp.70070
Cited by 4
AI Summary: OriGene's shRNA products (mouse Notum shRNA, TR512881, and control shRNA, TR30013) were used to generate stable cell lines for investigating the functional role of Notum in dentinogenesis in this study.
Snippet: nvitrogen), and 100 IU/mL of penicillin‐100 μg/mL of streptomycin (Invitrogen). To generate retroviral particles, shRNA against mouse Notum (TR512881) or control shRNA (TR30013) was purchased from OriGene Technologies (Rockville, MD, USA). The establishment of stable cell lines by viral transductions was performed as previously described (Choi et al. 2017). 2.6Statistical Analysis and Supporti
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Showing 1-1 of 1 papers.
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