Adnp Mouse shRNA Plasmid (Locus ID 11538)
Specifications
| Product Data | |
| Locus ID | 11538 |
|---|---|
| Synonyms | AA589558; mKIAA0784 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Adnp - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11538). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001310086, NM_001310088, NM_009628, NM_009628.1, NM_009628.2, NM_009628.3, BC050833, BC057666, BC090840, BC167195 |
| UniProt ID | Q9Z103 |
| Summary | This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-associated or hBRM factors (BAF) gene expression regulating complex, components of the protein translation machinery, and microtubule-associated proteins. This gene has been implicated in neuroprotection through various processes that include chromatin remodeling, splicing, cytoskeletal reorganization, and autophagy. Homozygous mutant knockout mice display embryonic lethality with defects in neural tube closure. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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