Abcb11 Mouse shRNA Plasmid (Locus ID 27413)
Specifications
| Product Data | |
| Locus ID | 27413 |
|---|---|
| Synonyms | ABC1; ABC16; Bs; Bsep; Lit; Lith1; PFI; PFIC2; PGY; PGY4; SPGP |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Abcb11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 27413). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_021022, NM_021022.1, NM_021022.2, BC156052, BC172671 |
| UniProt ID | Q9QY30 |
| Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt transporter in humans and mice. Mutations in the human gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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