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Marcks Mouse shRNA Plasmid (Locus ID 17118)

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SKU
TR512267
Marcks - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 17118
Synonyms Macs; PKCSL
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Marcks - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 17118). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC046601, NM_008538, NM_008538.1, NM_008538.2, BC002068, BC039911, BC055305
UniProt ID P26645
Summary MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Myristoylated Alanine-Rich protein Kinase C Substrate (MARCKS) expression modulates the metastatic phenotype in human and murine colon carcinoma in vitro and in vivo
Rombouts, Carloni, Mello et al
Cancer Lett (2013) 333 (2), 244-52 DOI: 10.1016/j.canlet.2013.01.040
Cited by 49
AI Summary: In this study, OriGene products—including MARCKS shRNA (TL514505) and MARCKS cDNA (RC200774)—were used to modulate MARCKS expression in colon carcinoma cell lines, enabling the investigation of MARCKS's role in cell motility, invasion, and metastasis.
Showing 1-1 of 1 papers.
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