Lin54 Mouse shRNA Plasmid (Locus ID 231506)
Specifications
| Product Data | |
| Locus ID | 231506 |
|---|---|
| Synonyms | AI461788 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Lin54 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 231506). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001115010, NM_001346583, NM_172714, NM_001359914, NM_172714.1, NM_172714.2, NM_172714.3, NM_172714.4, NM_001115010.1, BC055819, BC106126, BC125580, BC145025 |
| UniProt ID | Q571G4 |
| Summary | Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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