Col2a1 Mouse shRNA Plasmid (Locus ID 12824)
Specifications
| Product Data | |
| Locus ID | 12824 |
|---|---|
| Synonyms | Co; Col2; Col2a; Col2a-1; Del; Del1; Dmm; L; Lpk; M100413; Rgsc4; Rgsc8; Rgsc413; Rgsc856 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Col2a1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 12824). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC051383, BC052326, BC082331, NM_001113515, NM_031163, NM_031163.1, NM_031163.2, NM_031163.3, NM_001113515.1, NM_001113515.2, BC052326.1, BC030913 |
| UniProt ID | P28481 |
| Summary | This gene encodes the alpha-1 subunit of the fibril-forming type II collagen, the major component of cartilage and the vitreous humor of the eye. The encoded preproprotein forms homotrimeric, triple helical procollagen that undergoes proteolytic processing during fibirl formation. Mice harboring certain mutations in this gene exhibit severe chondrodysplasia characterized by short limbs and trunch, craniofacial deformities and cleft palate. A complete lack of the encoded protein in mice results in postnatal lethality. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. provided by RefSeq, Dec 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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