Daam1 Mouse shRNA Plasmid (Locus ID 208846)
Specifications
| Product Data | |
| Locus ID | 208846 |
|---|---|
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Daam1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 208846). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC076585, NM_001286452, NM_026102, NM_172464, NM_026102.1, NM_026102.2, NM_026102.3, NM_001286452.1, NM_172464.1, NM_172464.2, NM_172464.3, BC025638, BC032287, BC038403, BC047431, BC048856 |
| UniProt ID | Q8BPM0 |
| Summary | Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments (By similarity). Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (PubMed:26526197).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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