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Rtel1 Mouse shRNA Plasmid (Locus ID 269400)

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SKU
TR511295
Rtel1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 269400
Synonyms AI451565; AW540478; Rtel
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Rtel1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 269400). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC105578, NM_001001882, NM_001166665, NM_001166666, NM_001166667, NM_001166668, NR_030710, NM_001166665.1, NM_001001882.1, NM_001001882.2, NM_001001882.3, NM_001166666.1, NM_001166667.1, NM_001166668.1, BC144977, BC031201, BC057352, BC144978, BC145658, NM_001363071
UniProt ID Q0VGM9
Summary ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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