Otud5 Mouse shRNA Plasmid (Locus ID 54644)
Specifications
| Product Data | |
| Locus ID | 54644 |
|---|---|
| Synonyms | AA407879; AI553596; BB114028; DUBA; DXImx46e; Sfc7 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Otud5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54644). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC016529, BC051111, NM_001290536, NM_001290537, NM_138604, NM_138604.1, NM_138604.2, NM_138604.3, NM_001290537.1, NM_001290536.1 |
| UniProt ID | Q3U2S4 |
| Summary | Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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