Wwox Mouse shRNA Plasmid (Locus ID 80707)
Specifications
| Product Data | |
| Locus ID | 80707 |
|---|---|
| Synonyms | 5330426P09Rik; 9030416C10Rik; WOX1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Wwox - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 80707). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC014716, NM_019573, NM_019573.1, NM_019573.2, NM_019573.3, BM218596 |
| UniProt ID | Q91WL8 |
| Summary | Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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