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Ano6 Mouse shRNA Plasmid (Locus ID 105722)

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SKU
TR511035
Ano6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 105722
Synonyms 2900059G15Rik; AA407480; AW554778; F730003B03Rik; Tmem16f
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Ano6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 105722). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC060732, NM_001253813, NM_175344, NM_175344.1, NM_175344.2, NM_175344.3, NM_175344.4, NM_001253813.1, BC023745, BC052511
UniProt ID Q6P9J9
Summary Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets, osteoblasts and fetal thymocytes. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Calcium-dependent phospholipid scrambling by TMEM16F
Suzuki, Umeda, Sims et al
Nature (2010) 468 (7325), 834-8 DOI: 10.1038/nature09583
Cited by 1002
AI Summary: In this paper, OriGene's TMEM16F cDNA clone (Cat# SC119827) was used to express TMEM16F in cells, enabling the identification and functional analysis of TMEM16F as a key component in calcium-dependent phospholipid scrambling.
Showing 1-1 of 1 papers.
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