Lgmn Mouse shRNA Plasmid (Locus ID 19141)
Specifications
| Product Data | |
| Locus ID | 19141 |
|---|---|
| Synonyms | A; AEP; AI746452; AU022324; Pr; Prsc1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Lgmn - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 19141). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC132515, BC132519, NM_011175, NM_011175.1, NM_011175.2, NM_011175.3, NM_011175.4 |
| UniProt ID | O89017 |
| Summary | This gene encodes a member of the cysteine peptidase family C13 that plays an important role in the endosome/lysosomal degradation system. The encoded inactive preproprotein undergoes autocatalytic removal of the C-terminal inhibitory propeptide to generate the active endopeptidase that cleaves protein substrates on the C-terminal side of asparagine residues. Mice lacking the encoded protein exhibit defects in the lysosomal processing of proteins resulting in their accumulation in the lysosomes, and develop symptoms resembling hemophagocytic lymphohistiocytosis. provided by RefSeq, Aug 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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