Il33 Mouse shRNA Plasmid (Locus ID 77125)
Specifications
| Product Data | |
| Locus ID | 77125 |
|---|---|
| Synonyms | 9230117N10Rik; Il-33; Il1f11; NF-HEV |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Il33 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 77125). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC003847, NM_001164724, NM_133775, NM_001360725, NM_001164724.1, NM_133775.1, NM_133775.2, NM_133775.3 |
| UniProt ID | Q8BVZ5 |
| Summary | Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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