Dag1 Mouse shRNA Plasmid (Locus ID 13138)
Specifications
| Product Data | |
| Locus ID | 13138 |
|---|---|
| Synonyms | D9Wsu13; D9Wsu13e; DG; Dp71; Dp427 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dag1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 13138). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC007150, NM_001276481, NM_001276482, NM_001276485, NM_001276486, NM_001276492, NM_001276493, NM_001276494, NM_010017, NM_010017.1, NM_010017.2, NM_010017.3, NM_010017.4, NM_001276481.1, NM_001276482.1, NM_001276485.1, NM_001276486.1, NM_001276492.1, NM_001276493.1, NM_001276494.1 |
| UniProt ID | Q62165 |
| Summary | This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. A complete lack of the encoded protein in mice results in embryonic lethality due to the disorganization of Reichert's membrane. Chimeric mice deficient in the encoded protein overcome embryonic lethality but develop a progressive muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. provided by RefSeq, Nov 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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