Cobl Mouse shRNA Plasmid (Locus ID 12808)
Specifications
| Product Data | |
| Locus ID | 12808 |
|---|---|
| Synonyms | 4732460E13; C530045F18Rik; mKIAA0633 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Cobl - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 12808). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001282993, NM_001282994, NM_172496, NM_172496.1, NM_172496.2, NM_172496.3, NM_001282993.1, NM_001282994.1, BC145118, BC023264, BC025601, BC060061, BC145116, BC150706 |
| UniProt ID | Q5NBX1 |
| Summary | Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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