Atp6v1a Mouse shRNA Plasmid (Locus ID 11964)
Specifications
| Product Data | |
| Locus ID | 11964 |
|---|---|
| Synonyms | AI647066; Atp6a1; Atp6a2; Atp6v1a1; VA68; VPP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Atp6v1a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11964). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC038392, NM_007508, NM_001358203, NM_007508.2, NM_007508.3, NM_007508.4, NM_007508.5, BC050135, NM_001358204 |
| UniProt ID | P50516 |
| Summary | Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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