Msh5 Mouse shRNA Plasmid (Locus ID 17687)
Specifications
| Product Data | |
| Locus ID | 17687 |
|---|---|
| Synonyms | Mut5 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Msh5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 17687). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001146215, NM_013600, NR_130640, NR_130641, NM_013600.1, NM_013600.2, NM_013600.3, NM_001146215.1, NM_001146215.2, BC141113, BC030034, BC145406, BC145407 |
| UniProt ID | Q9QUM7 |
| Summary | This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogenesis in males and complete loss of ovarian structures in females. Mutations in a similar gene in humans have been shown to cause common variable immune deficiency (CVID) and immunoglobulin A deficiency. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jan 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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