Unc13d Mouse shRNA Plasmid (Locus ID 70450)
Specifications
| Product Data | |
| Locus ID | 70450 |
|---|---|
| Synonyms | 2610108D09Rik; Jinx; mFLJ00067; Munc13-4 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Unc13d - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 70450). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001009573, NM_001009573.1, NM_001009573.2, BC141289, BC046519 |
| UniProt ID | B2RUP2 |
| Summary | Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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