Pdgfra Mouse shRNA Plasmid (Locus ID 18595)
Specifications
| Product Data | |
| Locus ID | 18595 |
|---|---|
| Synonyms | AI115593; CD140; CD140a; Pdgfr; Pdgfr-2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pdgfra - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 18595). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC053036, NM_001083316, NM_011058, NR_144636, NM_001083316.1, NM_001083316.2, NM_011058.1, NM_011058.2, NM_011058.3, BC020405, BC037467 |
| UniProt ID | P26618 |
| Summary | This gene encodes a member of the receptor tyrosine kinase family of proteins. Binding of platelet-derived growth factor protein ligands to this receptor triggers receptor dimerization and autophosphorylation, resulting in the activation of several downstream signaling pathways. Signaling through the encoded receptor plays a role in gastrulation and the development of nearly all organ systems. Mice lacking a functional copy of this gene reportedly exhibit defects in lung, skeleton, testis and the central nervous system, and die soon after birth. Alternative splicing and intronic polyadenylation of gene transcripts have been implicated in muscle regeneration and fibrosis in adult mice. provided by RefSeq, Jan 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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