Unc5a Mouse shRNA Plasmid (Locus ID 107448)
Specifications
| Product Data | |
| Locus ID | 107448 |
|---|---|
| Synonyms | mKIAA1976; Unc5h1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Unc5a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 107448). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC058084, NM_001311128, NM_153131, NM_153131.1, NM_153131.2, NM_153131.3, BC058084.1, NM_153131.4 |
| UniProt ID | Q8K1S4 |
| Summary | Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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