Ano5 Mouse shRNA Plasmid (Locus ID 233246)
Specifications
| Product Data | |
| Locus ID | 233246 |
|---|---|
| Synonyms | 9330162L24; Gdd1; Tmem16e |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ano5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 233246). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC109163, NM_001271879, NM_177694, NR_073508, NM_177694.1, NM_177694.2, NM_177694.3, NM_177694.4, NM_177694.5, NM_177694.6, NM_001271879.1 |
| UniProt ID | Q75UR0 |
| Summary | This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to have little anion conductance activity. Elevated levels of this protein were found in dystrophic mice. In humans, mutations of this gene are associated with with musculoskeletal disorders such as myopathies, muscular dystrophy and gnathodiaphyseal dysplasia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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