Arhgap22 Mouse shRNA Plasmid (Locus ID 239027)
Specifications
| Product Data | |
| Locus ID | 239027 |
|---|---|
| Synonyms | B230341L19Rik; p68RacGAP; RHOGAP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Arhgap22 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 239027). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC038272, NM_153800, NM_153800.1, NM_153800.2, NM_153800.3, NM_153800.4 |
| UniProt ID | Q8BL80 |
| Summary | Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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