Prr7 Mouse shRNA Plasmid (Locus ID 432763)
Specifications
| Product Data | |
| Locus ID | 432763 |
|---|---|
| Synonyms | XM_484263 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Prr7 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 432763). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001030296, NM_001030296.1, NM_001030296.2, NM_001030296.3, NM_001030296.4, BC138854, BC138856 |
| UniProt ID | Q3V0I2 |
| Summary | Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (By similarity). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:27657535). Might promote apoptosis in T cells (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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