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Iffo1 Mouse shRNA Plasmid (Locus ID 320678)

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SKU
TR508354
Iffo1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 320678
Synonyms 4733401N06Rik; A930037G23Rik; HOM-TES-103; Iffo
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Iffo1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 320678). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC057601, NM_001039669, NM_001302778, NM_001302779, NM_178787, NR_126495, NM_178787.1, NM_178787.2, NM_178787.3, NM_178787.4, NM_178787.5, NM_178787.6, NM_001039669.1, NM_001039669.2, NM_001039669.3, NM_001302779.1, NM_001302778.1
UniProt ID Q8BXL9
Summary Nuclear matrix protein involved in the immobilization of broken DNA ends and the suppression of chromosome translocation during DNA double-strand breaks (DSBs) (PubMed:31548606). Interacts with the nuclear lamina component LMNA, resulting in the formation of a nucleoskeleton that will relocalize to the DSB sites in a XRCC4-dependent manner and promote the immobilization of the broken ends, thereby preventing chromosome translocation (PubMed:31548606). Acts as a scaffold that allows the DNA repair protein XRCC4 and LMNA to assemble into a complex at the DSB sites (PubMed:31548606).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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