Atg9a Mouse shRNA Plasmid (Locus ID 245860)
Specifications
| Product Data | |
| Locus ID | 245860 |
|---|---|
| Synonyms | Apg9l1; Atg9; Atg9l1; AU019532 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Atg9a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 245860). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC079884, NM_001003917, NM_001288612, NM_001288613, NR_109938, NM_001003917.1, NM_001003917.2, NM_001003917.3, NM_001003917.4, NM_001288613.1, NM_001288612.1, BC034139, BC056488, BC082307 |
| UniProt ID | Q68FE2 |
| Summary | Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). Required for carbonyl cyanide m-chlorophenylhydrazone (CCCP)-induced ATG8 family proteins lipidation, a key autophagy step.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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