Wdr63 Mouse shRNA Plasmid (Locus ID 242253)
Specifications
| Product Data | |
| Locus ID | 242253 |
|---|---|
| Synonyms | 4931433A13Rik; IC140; Ida7 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Wdr63 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 242253). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC132106, BC132108, NM_172864, NM_172864.1, NM_172864.2, NM_172864.3, BC158119 |
| UniProt ID | B2RY71 |
| Summary | Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (By similarity). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (PubMed:25498833).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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