Fgl1 Mouse shRNA Plasmid (Locus ID 234199)
Specifications
| Product Data | |
| Locus ID | 234199 |
|---|---|
| Synonyms | Mfire1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Fgl1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 234199). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC021946, BC029734, NM_145594, NM_145594.1, NM_145594.2, BC029734.1 |
| UniProt ID | Q71KU9 |
| Summary | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). In addition to its role in inhibiting inflammatory immune responses, also plays a role in hepatocytes (By similarity). Under normal physiological conditions, primarily secreted from hepatocytes and contributes to its mitogenic and metabolic functions (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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