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Arfgap1 Mouse shRNA Plasmid (Locus ID 228998)

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SKU
TR506827
Arfgap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 228998
Synonyms AI115377; Arf1gap
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Arfgap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 228998). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC052922, BC059817, NM_001177706, NM_001177707, NM_001177708, NM_001177709, NM_001177710, NM_145760, NM_145760.1, NM_145760.2, NM_145760.3, NM_001177706.1, NM_001177707.1, NM_001177708.1, NM_001177709.1, NM_001177710.1, BC016228, BC027794, NM_001363035, NM_001363036, NM_001363037, NM_001177706.2
UniProt ID Q9EPJ9
Summary GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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