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Dclre1c Mouse shRNA Plasmid (Locus ID 227525)

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SKU
TR506772
Dclre1c - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 227525
Synonyms 9930121L06Rik; A; AI661365; Art; Snm1l
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Dclre1c - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 227525). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC108935, NM_001110214, NM_001302674, NM_001302684, NM_146114, NM_175683, NM_175683.1, NM_175683.2, NM_175683.3, NM_175683.4, NM_001110214.1, NM_146114.1, NM_146114.2, NM_146114.3, NM_001302674.1, NM_001302684.1, BC030672, BC030680
UniProt ID Q8K4J0
Summary This gene encodes a member of the SNM1 family of nucleases and is involved in V(D)J recombination and DNA repair. This protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Homozygous knockout mice for this gene exhibit severe combined immunodeficiency with sensitivity to ionizing radiation. Mutations in this gene in humans can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Nov 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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