Lzts2 Mouse shRNA Plasmid (Locus ID 226154)
Specifications
| Product Data | |
| Locus ID | 226154 |
|---|---|
| Synonyms | BC014695; LAPSER1; mKIAA1813 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Lzts2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 226154). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC014695, BC092263, NM_001130525, NM_001130526, NM_145503, NM_001130525.1, NM_001130526.1, NM_145503.1, NM_145503.2 |
| UniProt ID | Q91YU6 |
| Summary | Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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