D17Wsu92e Mouse shRNA Plasmid (Locus ID 224647)
Specifications
| Product Data | |
| Locus ID | 224647 |
|---|---|
| Synonyms | AU020189; C030010A15; C80239 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | D17Wsu92e - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 224647). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC132324, BC132326, NM_001033279, NM_001044719, NM_001271511, NM_001033279.1, NM_001033279.2, NM_001033279.3, NM_001044719.1, NM_001044719.2, NM_001271511.1, BC145403, BC137573, BC137576 |
| UniProt ID | Q3TT38 |
| Summary | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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