March6 Mouse shRNA Plasmid (Locus ID 223455)
Specifications
| Product Data | |
| Locus ID | 223455 |
|---|---|
| Synonyms | 3830408G03; F830029L24Rik; mKIAA0597 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | March6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 223455). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC059190, NM_172606, NM_172606.1, NM_172606.2, BC027068, BC031721, BC037454, BC039776, BC048816 |
| UniProt ID | Q6ZQ89 |
| Summary | E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation. Promotes ubiquitination of DIO2, leading to its degradation. Promotes ubiquitination of SQLE, leading to its degradation. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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