Mylk3 Mouse shRNA Plasmid (Locus ID 213435)
Specifications
| Product Data | |
| Locus ID | 213435 |
|---|---|
| Synonyms | D830007F02Rik; MLCK |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Mylk3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 213435). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001297612, NM_175441, NM_175441.1, NM_175441.2, NM_175441.3, NM_175441.4, NM_175441.5, NM_001297612.1, BC137983, BC145079 |
| UniProt ID | Q3UIZ8 |
| Summary | Kinase that phosphorylates MYL2 in vitro. Has been proposed to be calmodulin-dependent (PubMed:17885681), although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin (PubMed:18202317). Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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