Tlr3 Mouse shRNA Plasmid (Locus ID 142980)
Specifications
| Product Data | |
| Locus ID | 142980 |
|---|---|
| Synonyms | AI957183 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Tlr3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 142980). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC099937, NM_126166, NM_001357316, NM_001357317, NM_126166.1, NM_126166.2, NM_126166.3, NM_126166.4, BC023850, NM_126166.5 |
| UniProt ID | Q99MB1 |
| Summary | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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