Nabp1 Mouse shRNA Plasmid (Locus ID 109019)
Specifications
| Product Data | |
| Locus ID | 109019 |
|---|---|
| Synonyms | 4930434H03Rik; 4930442A21Rik; 4930488J04Rik; 4933440J18Rik; 5830411E10Rik; AI852561 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Nabp1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 109019). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC095967, BC131923, BC132532, NM_001310548, NM_001310549, NM_028696, NM_028696.1, NM_028696.2, NM_028696.3, BC027371 |
| UniProt ID | Q8BGW5 |
| Summary | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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