Ovol2 Mouse shRNA Plasmid (Locus ID 107586)
Specifications
| Product Data | |
| Locus ID | 107586 |
|---|---|
| Synonyms | 1700108N11Rik; 1810007D21Rik; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; Zfp339 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ovol2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 107586). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC031771, BC057210, BC094445, NM_026924, NM_152947, NM_026924.2, NM_026924.3, NM_152947.1, NM_152947.2 |
| UniProt ID | Q8CIV7 |
| Summary | Zinc-finger transcription repressor factor (PubMed:15225875, PubMed:23319585). Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (PubMed:24735878, PubMed:24735879). Positively regulates neuronal differentiation (PubMed:16423343, PubMed:23319585). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1 (By similarity). Important for the correct development of primordial germ cells in embryos (PubMed:28059165).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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