Lrrc19 Mouse shRNA Plasmid (Locus ID 100061)
Specifications
| Product Data | |
| Locus ID | 100061 |
|---|---|
| Synonyms | 9130022A01Rik; AI314124; AL022954; AW261791 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Lrrc19 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 100061). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC061228, NM_175305, NM_001356281, NM_175305.1, NM_175305.2, NM_175305.3, NM_175305.4, BC029715, NM_175305.5 |
| UniProt ID | Q8BZT5 |
| Summary | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of proinflammatory cytokines (PubMed:26776522, PubMed:19679103, PubMed:25026888). In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances (PubMed:25026888). In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (PubMed:26776522).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.