Pacsin3 Mouse shRNA Plasmid (Locus ID 80708)
Specifications
| Product Data | |
| Locus ID | 80708 |
|---|---|
| Synonyms | 4921507A02Rik; 6330413E15Rik; AW413130 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pacsin3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 80708). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC003884, NM_001289677, NM_001289678, NM_028733, NM_030880, NM_028733.1, NM_028733.2, NM_028733.3, NM_028733.4, NM_001289677.1, NM_001289678.1, NM_030880.1, NM_030880.3 |
| UniProt ID | Q99JB8 |
| Summary | Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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